Lung cancer develops when lung cells undergo genetic alterations, such as fusions, deletions, or mutations. These changes cause abnormal growths, typically nodules, which often signal that the cancer has spread. Knowing the warning signs and symptoms of lung cancer is beneficial for all adults, smokers or not. Here's what to look out for. Chest Pains or Aches Pain from lung cancer is frequently caused by a tumor that presses on nerves or tightens the chest. Lung cancer often manifests as chest pain, particularly during deep breathing, coughing, or laughing. Hoarseness Chronic coughing or a tumor that interferes with the vocal cords can cause a raspy voice in people with lung cancer. A Chronic Cough Early-stage lung cancer usually impacts how your respiratory system functions. A persistent horse cough that progressively gets worse can be a symptom of lung cancer. Shortness of Breath Lung cancer can narrow the airways, leading to difficulty breathing. A tumor puts pressure on the lungs, causing the respiratory system to become inflamed and agitated.